What is Umckaloabo Plant Extract?

The usable part of Umckaloabo is the root. Active constituents are thought to be coumarins; hydrolysable tannins such as catechin, gallocatechin, gallic acid and other polyphenols; and proanthocyanidins. For bronchitis and other respiratory disorders, Umckaloabo is believed to have antimicrobial and immunostimulatory effects. Umckaloabo is used orally for treating respiratory infections such as bronchitis, pharyngitis, the common cold, tonsilitis, sinusitis, pharyngitis, and tonsillopharyngitis. It is also used for tuberculosis, herpes, gonorrhea, diarrhea, and dysentery.

Also known as:  African Geranium, EPs 7630, Geranien, Geranio Sudafricano, Geranium, Géranium d’Afrique, Géranium d’Afrique du Sud, Géranium du Cap, Geranium Root, Ikhubalo, Icwayiba, i-Yeza lezikali, Kalwerbossi, Khoaara e Nyenyane, Pelargonien, Pelargonio Sudafricano, Pelargonium Root, Pélargonium d’Afrique, Pélargonium du Cap, Rabas, Rabassam, Racine de Géranium, Racine de Pélargonium, South African Geranium, Uvendle

Diseases and Conditions

Umckaloabo is likely effective for bronchitis, and possibly effective for tonsillopharyngitis. There is insufficient information on the effectiveness of Umckaloabo for the common cold and sinusitis, as well as its other uses.

Safety

Umckaloabo is likely safe when used orally in the short term. Not much is known about the safety of Umckaloabo when used orally in the long term.

Children may safely use Umckaloabo orally under the supervision of a physician.

There is insufficient information on the safety of Umckaloabo for pregnant and breastfeeding women, so it is best to avoid.

Umckaloabo is generally well-tolerated if used for short periods of time.

Rare but possible side effects include the following:

  • Itching
  • Skin rashes
  • Angioedema
  • Conjunctivitis
  • Gastrointestinal upset

Umckaloabo contains coumarin, which may decrease platelet aggregation and increase the risk for spontaneous bleeding; discontinue use at least two weeks before surgery.

Medication Interactions

Umckaloabo may interfere with the following medications:

  • Anticoagulant and antiplatelet drugs, such as:
    • Aspirin
  • Clopidogrel (Plavix)
  • Nonsteroidal anti-inflammatory drugs (NSAIDs), such as:
    • Diclofenac (Voltaren, Cataflam, others)
    • Ibuprofen (Advil, Motrin, others)
    • Naproxen (Anaprox, Naprosyn, others)
  • Dalteparin (Fragmin)
  • Enoxaparin (Lovenox)
  • Heparin
  • Warfarin (Coumadin)
  • Immunosuppressant drugs, such as:
    • Azathioprine (Imuran)
    • Basiliximab (Simulect)
    • Cyclosporine (Neoral, Sandimmune)
    • Daclizumab (Zenapax)
    • Muromonab-CD3 (OKT3, Orthoclone OKT3)
    • Mycophenolate (CellCept)
    • Tacrolimus (FK506, Prograf)
    • Sirolimus (Rapamune)
    • Prednisone (Deltasone, Orasone)
    • Other corticosteroids (glucocorticoids)

Supplement and Food Interactions

Umckaloabo may interfere with the following supplements, herbs, and foods:

  • Anticoagulant/antiplatelet herbs and supplements, such as:
    • Angelica
    • Clove
    • Danshen
    • Garlic
    • Ginger
    • Ginkgo
    • Panax ginseng
    • Horse chestnut
    • Turmeric

Dosage

The correct dosage of any supplement requires a comprehensive analysis of many factors including your age, sex, health conditions, DNA, andlifestyle.

Anecdotal information suggests taking one tablet (ten, twenty, or thirty milligrams), with food, three times daily for up to ten days. Thirty drops of a specific extract (EPs 7630®, Schwabe GmBh, Germany) three times daily for ten days has also been used for various respiratory tract conditions. For acute bronchitis, thirty drops of EPs 7630® solution (four and one-half milliliters total over three doses) (Umckaloabo, EPs 7630®, Schwabe GmBh, Germany), three times daily for seven to fourteen days has been used. For the common cold, thirty drops of Pelargonium sidoides extract three times daily (four and one-half milliliters total) for up to ten days has been used. For acute pharyngitis (acute non-group A beta-hemolytic streptococcus tonsillopharyngitis), twenty drops, three times daily (approximately three milliliters total) of EPs 7630® solution (Umckaloabo, EPs 7630®, Schwabe GmBh, Germany) for seven days in children aged six to ten years has been used.

Foods

There is insufficient evidence to determine if Umckaloabo can be found in foods.

 

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