Discover How to Eat, Exercise, and
Supplement Right
For Your DNA


Diiodothyronine is a metabolite of thyroxine (T4) and triiodothyronine (T3) and is produced in small amounts by the thyroid gland. Research suggests that diiodothyronine may increase the rate of oxygen consumption by the mitochondria and liver. Other research suggests it might increase the activity of enzymes such as cytochrome oxidase and alpha-glycerophosphate dehydrogenase. It also might stimulate growth hormone secretion and increase the basal metabolic rate. Diiodothyronine is used orally for weight loss, hyperlipidemia, and body building.

Also known as:  3, 5 diiodothyronine, 3, 5-L-diiodothryonine, 3, 5-T2, Diyodotironina, T2, T-2

Diseases and Conditions

There is insufficient reliable information available about the effectiveness of diiodothyronine for weight loss, hyperlipidemia, and body building.


There is insufficient information on the safety of diiodothyronine for adults, children, pregnant and breastfeeding women; best to avoid. No side effects have been reported with diiodothyronine use.

Medication Interactions

There are no known medication interactions for diiodothyronine.

Supplement and Food Interactions

There are no known supplement, herb, or food interactions for diindothyronine.


There is insufficient reliable evidence available to determine a dosage for diiodothryonine.


Diiodothyronine is not found in foods.

Interested in Learning Which
Supplements are Right for You?



  1. https://naturalmedicines.therapeuticresearch.com/references.aspx?productid=1136
  2. http://naturaldatabase.therapeuticresearch.com/nd/Search.aspx?cs=&s=ND&pt=100&id=1136&fs=ND&searchid=61465981
  3. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292545/

Discover How to Eat, Exercise, and SupplementRight For Your DNA