Coriolus Mushroom

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Coriolus mushroom, orcoriolusversicolor, is a mushroom with a long history in folk medicine. Researchers are just beginning to isolate and identify substances in coriolus that have pharmacological value. Coriolus contains several polysaccharides, including polysaccharide peptide (PSP) and polysaccharide krestin (PSK), shown to have antitumor and immunomodulating effects.

Coriolus mushroom or its derivatives are used for the following:

  • Stimulating the immune system
  • Herpes
  • Chronic fatigue syndrome
  • Hepatitis
  • Pulmonary disorders
  • Reducing phlegm
  • Improving body building
  • Increasing energy
  • Curing ringworm and impetigo
  • Upper respiratory, urinary, and digestive tract infections
  • Curing liver disorders
  • Ameliorating the toxic effects and pain of chemotherapy and radiation therapy
  • Promoting curative effect of chemotherapy
  • Prolonging life and raising the quality of life
  • Increasing appetite
  • Improving the effectiveness of cancer chemotherapy

Coriolus might also have activity against the human immunodeficiency virus (HIV).

Also known as:  Bolet à Couleurs Variées, Bolet Versicolore, Champignon Coriolus, Champignon de Queue de Dinde, Coriolus, Hongo Coriolus, Kawaratake, Krestin, Polypore à Couleurs Variées, Polypore Versicolor, Polysaccharide-K, Polysaccharide Krestin, Polysaccharide Peptide, Polysaccharopeptide, PSK, PSP, Turkey Tail, Yun Zhi, Yun-Zhi (cloud mushroom)

Diseases and Conditions

Coriolus mushroom is possibly effective for cancer. Taking polysaccharide krestin (PSK), a constituent of coriolus mushroom, orally has shown to improve response and survival in some patients with cancer. PSK is given as a biologic response modifier (such as interferon or interleukin-2) as an adjunct to standard chemotherapy, and has been used in Japan for several decades for breast cancer, esophageal cancer, gastric cancer, lung cancer, hepatic cancer, colorectal cancer, nasopharyngeal cancer, and leukemia. There is insufficient reliable information available about the effectiveness of coriolus mushroom for its other uses.

Safety

Coriolus mushroom may be safe when taken orally and appropriately.

There is insufficient information on the safety of coriolus mushroom for children, pregnant, and breastfeeding women.

Polysaccharide krestin (PSK), a constituent of coriolus mushroom, is relatively nontoxic when taken in the appropriate doses. However, toxicity is still possible; other side effects associated with PSK include the following:

  • Darkened fingernails
  • Gastrointestinal upset
  • Leukopenia
  • Liver damage

Medication Interactions

There are no known medication interactions for coriolus mushroom.

Supplement and Food Interactions

There are no known supplement, herb, or food interactions for coriolus mushroom.

Dosage

The correct dosage of any supplement requires a comprehensive analysis of many factors including your age, sex, health conditions, DNA, andlifestyle. 

The recommended dosage for coriolus mushroom depends on what it is being used for.

  • For breast cancer (adjuvant), the recommended dosage is three grams of PSK taken alone or with hormone therapy, chemotherapy, or surgery.
  • For colorectal cancer (adjuvant), the recommended dosage is three grams of PSK taken daily in addition to standard treatment for up to two years.
  • For esophageal cancer (adjuvant), the recommended dosage is three grams of PSK daily in combination with chemotherapy.
  • For gastric cancer (adjuvant), the recommended dosage is three grams of PSK taken daily in addition to standard treatment.
  • For leukopenia (adjuvant), the recommended dosage is three grams of PSK daily in combination with chemotherapy.
  • For liver cancer (adjuvant), the recommended dosage is three grams of PSK taken daily in combination with tegafur.
  • For lung cancer (adjuvant), the recommended dosage is chemotherapy plus three grams of PSK daily.
  • For nasopharyngeal carcinoma (adjuvant), the recommended dosage is one gram of PSK taken three times daily for at least one month upon completion of primary treatment for tumors.

Foods

Coriolus mushroom is not found in foods.

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References

  1. http://naturaldatabase.therapeuticresearch.com/nd/Search.aspx?cs=&s=ND&pt=100&id=648&fs=ND&searchid=61486083
  2. https://naturalmedicines.therapeuticresearch.com/references.aspx?productid=648
  3. http://www.medicinenet.com/coriolus_mushroom/supplements-vitamins.htm

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