What are Caprylic Acid Sources and Side Effects?

Caprylic acid, also known as octanoic acid, is found naturally in the milk of various mammals and is a minor component of coconut oil and palm kernel oil. Caprylic acid is used for seizures, hypoalbuminemia in hemodialysis patients, digestive disorders such as dysbiosis, lipid malabsorption, and chylothorax.

Also known as:  Octanoate

Diseases and Conditions

There is insufficient information on the effectiveness of caprylic acid for for seizures, hypoalbuminemia in hemodialysis patients, digestive disorders such as dysbiosis, lipid malabsorption, and chylothorax.

Safety

Caprylic acid is likely safe when consumed orally from dietary sources. Caprylic acid has achieved a Generally Recognized As Safe (GRAS) status in the United States if used orally in appropriate doses.

Individuals with medium-chain acyl-CoA dehydrogenase (MCAD) deficiency should not consume caprylic acid.

There is insufficient information on the safety of caprylic acid on children; for pregnant and breastfeeding women there is also a lack of information – best to avoid consuming in amounts larger than those found in food.

Common side effects reported from caprylic acid use are gastrointestinal in nature; these include diarrhea, bloating, and nausea.

Dermatologic sensitivity to caprylic acid is more common among Asians as opposed to Caucasians. When used as part of a ketogenic diet, other side effects may include hypocalcemia, increased rate of infection, drowsiness, lethargy, kidney stones, and acidosis.

Medication Interactions

Concomitant use of caprylic acid with antihypertensive drugs such as captopril (Capoten), enalapril (Vasotec), losartan (Cozaar), valsartan (Diovan), diltiazem (Cardizem), amlodipine (Norvasc), hydrochlorothiazide (HydroDIURIL), furosemide (Lasix); non-steroidal anti-inflammatory drugs such as diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn); and warfarin may have additive effects.

Supplement and Food Interactions

Concomitant use of caprylic acid with hypotensive effects such as andrographis, casein peptides, cat’s claw, coenzyme Q-10, fish oil, L-arginine, lyceum, stinging nettle, theanine may lower blood pressure.

Dosage

There is insufficient reliable evidence available to determine a dosage for caprylic acid.

Foods

Caprylic acid is found naturally in the milk of various mammals and is a minor component of coconut oil and palm kernel oil.

 

Caprylic acid, also known as octanoic acid, is found naturally in the milk of various mammals and is a minor component of coconut oil and palm kernel oil. Caprylic acid is used for seizures, hypoalbuminemia in hemodialysis patients, digestive disorders such as dysbiosis, lipid malabsorption, and chylothorax.

Also known as:  Octanoate

Diseases and Conditions

There is insufficient information on the effectiveness of caprylic acid for for seizures, hypoalbuminemia in hemodialysis patients, digestive disorders such as dysbiosis, lipid malabsorption, and chylothorax.

Safety

Caprylic acid is likely safe when consumed orally from dietary sources. Caprylic acid has achieved a Generally Recognized As Safe (GRAS) status in the United States if used orally in appropriate doses.

Individuals with medium-chain acyl-CoA dehydrogenase (MCAD) deficiency should not consume caprylic acid.

There is insufficient information on the safety of caprylic acid on children; for pregnant and breastfeeding women there is also a lack of information – best to avoid consuming in amounts larger than those found in food.

Common side effects reported from caprylic acid use are gastrointestinal in nature; these include diarrhea, bloating, and nausea.

Dermatologic sensitivity to caprylic acid is more common among Asians as opposed to Caucasians. When used as part of a ketogenic diet, other side effects may include hypocalcemia, increased rate of infection, drowsiness, lethargy, kidney stones, and acidosis.

Medication Interactions

Concomitant use of caprylic acid with antihypertensive drugs such as captopril (Capoten), enalapril (Vasotec), losartan (Cozaar), valsartan (Diovan), diltiazem (Cardizem), amlodipine (Norvasc), hydrochlorothiazide (HydroDIURIL), furosemide (Lasix); non-steroidal anti-inflammatory drugs such as diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn); and warfarin may have additive effects.

Supplement and Food Interactions

Concomitant use of caprylic acid with hypotensive effects such as andrographis, casein peptides, cat’s claw, coenzyme Q-10, fish oil, L-arginine, lyceum, stinging nettle, theanine may lower blood pressure.

Dosage

There is insufficient reliable evidence available to determine a dosage for caprylic acid.

Foods

Caprylic acid is found naturally in the milk of various mammals and is a minor component of coconut oil and palm kernel oil.

References

  • https://naturalmedicines.therapeuticresearch.com/references.aspx?productid=1465
  • https://pubchem.ncbi.nlm.nih.gov/compound/octanoic_acid
  • http://naturaldatabase.therapeuticresearch.com/nd/Search.aspx?cs=&s=ND&pt=100&id=1465&fs=ND&searchid=61500687

 

Anxiety concerns? Want to lose weight?

Utilize your DNA to take the guesswork out of achieving your goals.

Responses

avatar

Want to get fresh news? Subscribe to Blog!

Get updates of the most trendy news delivered to your email

Want to get fresh news?

Subscribe to Vitagene updates and know more about vitamins