What is Cola Nut Bean?

Cola nut is available as several different species from trees growing in Cameroon and the Democratic Republic of the Congo, and cola vera is generally preferred over other Cola species for its medicinal purposes. Cola nut is used orally for short-term relief of mental and physical fatigue and depressive states, especially those associated with general muscle weakness. It is also used orally for the following conditions:

  • Chronic fatigue syndrome (CFS)
  • Melancholy
  • Atony
  • Exhaustion
  • Dysentery
  • Atonic diarrhea
  • Weight loss
  • Migraines

Cola nut is also used as a flavoring ingredient.

Also known as:  Arbre à Cola, Arbre à Kola, Bissey Nut, Bissy Nut, Guru Nut, Gworo, Kola Nut, Kolatier, Noix de Cola, Noix de Gourou, Noix de Kola, Noix du Kolatier, Noix de Soudan, Noix du Soudan, Nuez de Cola, Soudan Coffee

Diseases and Conditions

There is insufficient reliable information available about the effectiveness of cola nut on the following:

  • Short-term relief of mental and physical fatigue and depressive states
  • Chronic fatigue syndrome (CFS)
  • Melancholy
  • Atony
  • Exhaustion
  • Dysentery
  • Atonic diarrhea
  • Weight loss
  • Migraines


Cola nut may be safe when consumed in amounts commonly found in food, orally, and for up to 12 weeks. Cola nut has achieved a Generally Recognized As Safe (GRAS) status in the United States.

It is likely unsafe to consume high amounts of cola nut for a prolonged period of time because it contains caffeine.

Chewing cola nut has been linked to an increased risk of mouth and gastrointestinal cancer.

The fatal dose of cola nut is estimated to be at 10-14 grams; toxicity can occur even at lower doses if an individual smokes, has had caffeine use, or is older.

Children may safely consume cola nut orally in food amounts.

Pregnant and breastfeeding women may safely consume cola nut orally in food amounts, but it is unsafe for them when consumed in high amounts; best to avoid or use under the supervision of a physician.

Possible side effects of cola nut include the following:

  • Anxiety
  • Insomnia
  • Gastrointestinal problems
  • Nervousness
  • Oral blisters
  • Tremors

Cola nut may affect blood glucose levels during surgery; discontinue use at least 2 weeks before the procedure. Individuals with anxiety, diabetes, bleeding disorders, cardiac conditions, glaucoma, hypertension, irritable bowel syndrome, and osteoporosis should avoid cola nut or consume with caution.

Medication Interactions

Cola nut charcoal has minor interactions with the following medications:

  • Antidiabetes drugs
  • Cimetidine
  • Contraceptive drugs
  • Fluconazole
  • Mexiletine
  • Terbinafine

Cola nut has moderate interactions with the following medications:

  • Adenosine
  • Alcohol
  • Alendronate
  • Anticoagulant/antiplatelet drugs
  • Beta-adrenergic agonists
  • Clozapine
  • Dipyridamol
  • Disulfiram
  • Estrogens
  • Fluvoxamine
  • Levothyroxine
  • Lithium
  • Monoamine oxidase inhibitors
  • Pentobarbital
  • Phenothiazines
  • Phenylpropanolamine
  • Quinolone antibiotics
  • Riluzole
  • Stimulant drugs
  • Theophylline
  • Tricyclic antidepressants
  • Verapamil

Cola nut should be used with caution with the above drugs.

Cola nut has a major interactions with the following medications:

  • Ephedrine
  • Amphetamines
  • Cocaine

Cola nut should not be taken with these drugs.

Supplement and Food Interactions

Cola nut may have interactions with the following supplements and herbs:

  • Anticoagulant/antiplatelet herbs and supplements
  • Bitter orange
  • Any herbs or supplements containing caffeine
  • Calcium
  • Creatine
  • Ephedra
  • Magnesium

Concomitant use of herbs and supplements that affect platelet aggregation with caffeine could theoretically increase the risk of bleeding in some people. Bitter orange in combination with caffeine or caffeine-containing herbs can increase blood pressure and heart rate. Concomitant use of cola nut and caffeine-containing herbs/supplements constitutes therapeutic duplication (due to the caffeine contained in cola nut) which increases the risk of caffeine-related adverse effects. High caffeine intake from cola nut increases urinary calcium excretion. There is some concern that combining caffeine with ephedra, and creatine might increase the risk of serious adverse effects. Lastly, consuming large amounts of cola nut can increase excretion of magnesium.


The correct dosage of any supplement requires a comprehensive analysis of many factors including your age, sex, health conditions, DNA, andlifestyle.

The recommended dosage of cola nut depends on which form it is in when administered.

  • As a liquid extract, the recommended daily dose is two to six grams. The liquid extract is a one to one ratio solution of sixty percent alcohol and cola nut and should be taken three times daily.
  • As a tincture, the recommended daily dose is ten to thirty grams. Tinctures in a one to five ratio solution of sixty percent alcohol along with one to four milliliters of cotyledons are recommended three times daily.
  • As powdered cotyledons, the recommended daily dose is one to three grams as a decoction, liquid extract, or tincture. A decoction should be made by boiling one to two teaspoons in one cup of water and taken three times daily.


Cola nut is used as a flavoring ingredient in foods and beverages.


  • http://naturaldatabase.therapeuticresearch.com/nd/Search.aspx?cs=&s=ND&pt=100&id=937&fs=ND&searchid=61669086
  • https://naturalmedicines.therapeuticresearch.com/references.aspx?productid=937


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